MSDS: 3-Bromochlorobenzene

Identification

Product Name: 3-Bromochlorobenzene
Chemical Family: Halogenated aromatic
Synonyms: m-Bromochlorobenzene; 1-Bromo-3-chlorobenzene
Chemical Formula: C6H4BrCl
Molecular Weight: 191.45 g/mol
CAS Number: 591-17-3
Recommended Use: Laboratory chemicals, synthesis of chemical products
Supplier/Manufacturer: Check packaging for supplier details
Emergency Contact Number: Refer to local regulations and packaging label

Hazard Identification

GHS Classification: Acute toxicity (oral, dermal), Skin irritation, Eye irritation
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and serious eye irritation, may cause respiratory irritation
Pictograms: Exclamation mark symbol
Routes of Entry: Inhalation, skin and eye contact, ingestion
Potential Health Effects: Burning sensation on skin and eyes, headache, nausea, dizziness with inhalation, stomach upset if ingested
Precautionary Statements: Avoid contact with eyes, skin and clothing, do not breathe dust or vapors, use only outdoors or in well-ventilated area, wash thoroughly after handling
NFPA Rating: Health: 2; Flammability: 1; Reactivity: 0
Environmental Hazards: Toxic to aquatic life in high concentrations

Composition / Information on Ingredients

Chemical Name: 3-Bromochlorobenzene
Concentration: >99% (pure compound for most lab use)
Other Components: Trace residual solvents or impurities possible based on supplier batch, consult supplier COA for trace data
CAS Number: 591-17-3
EC Number: 209-702-8
Impurities: Not expected above 0.1% under regular controlled production

First Aid Measures

Inhalation: Move to fresh air, keep at rest in position comfortable for breathing, seek medical attention if symptoms develop or persist; oxygen or CPR as needed
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water and mild soap for at least 15 minutes, consult a doctor if irritation occurs
Eye Contact: Flush with plenty of clean water for at least 15 minutes, holding eyelids open, get medical attention straight away
Ingestion: Rinse mouth, do not induce vomiting, drink water only if fully conscious, get immediate medical assistance
Most Important Symptoms/Effects: Eye, skin, and respiratory tract irritation, headache, nausea; symptoms can be delayed
Note to Physician: Treat symptomatically and provide supportive care

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder or appropriate foam
Unsuitable Extinguishing Media: Direct water stream may spread burning liquid
Hazards from Combustion: Emits toxic and corrosive fumes of hydrogen chloride, hydrogen bromide, and phosgene on burning
Protective Equipment and Precautions: Wear self-contained breathing apparatus and full protective gear, keep personnel upwind and out of low areas
Special Procedures: Cool fire-exposed containers with water spray to prevent rupture from heat, avoid breathing gases/vapors/fumes, evacuate fire area if safe to do so

Accidental Release Measures

Personal Precautions: Wear protective clothing, gloves, goggles, and suitable respirator in poorly ventilated areas
Environmental Precautions: Prevent further leakage or spillage if safe to do so, keep out of drains, surface and ground water
Spill Cleanup Methods: Absorb with inert material (sand, earth, vermiculite), collect spilled material in sealable container for disposal, wash affected area with soap and water
Decontamination Procedures: Scrub surface with detergent and plenty of water after removal
Disposal: Do not flush to sewer, see Disposal Considerations for proper handling
Notification Procedures: Notify authorities if large spills enter waterways or soil

Handling and Storage

Safe Handling Practices: Avoid breathing vapors, prevent skin and eye contact, work in well-ventilated or exhaust-vented spaces, use spark-proof tools and explosion-proof equipment
Advice on General Occupational Hygiene: Do not eat, drink, or smoke during use; keep work clothing separate; wash hands after handling
Storage Conditions: Store in tightly closed original container in cool, dry, and well-ventilated place, away from incompatible materials like strong acids and oxidizers
Storage Incompatibilities: Not to be stored with strong oxidizing agents, halogens, or bases
Shipping Information: See Transport Information for specifics
Special Packaging Requirements: Use containers resistant to brominated organics, labeled in accordance with local regulations

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established regulatory exposure limits, good ventilation and hygiene practices reduce risk
Engineering Controls: Work in fume hood, use local mechanical exhaust or ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), splash-proof goggles or face shield, lab coat or chemical suit, suitable respiratory protection if exposure risk increases
Environmental Controls: Prevent splash generation, contain contaminated runoff
Hygiene Measures: Remove contaminated clothing and wash skin promptly; clean work area after handling

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid or crystalline solid depending on temperature
Odor: Aromatic, strong halogenated solvent-like
pH: Not water soluble, not applicable
Melting Point: 27–30°C
Boiling Point: 205–207°C
Flash Point: 85°C (closed cup)
Evaporation Rate: Lower than water
Flammability: Slightly combustible
Vapor Pressure: 0.3 mmHg at 20°C
Vapor Density: 6.6 (air = 1)
Relative Density: 1.6 g/cm³ at 25°C
Solubility: Insoluble in water, soluble in organic solvents (ethanol, ether, benzene)
Partition Coefficient (log Kow): 3.7
Autoignition Temperature: Above 510°C
Decomposition Temperature: Not available

Stability and Reactivity

Chemical Stability: Stable under normal storage and use conditions
Conditions to Avoid: Exposure to heat, open flames, sparks, strong sunlight
Materials to Avoid: Oxidizing agents (may cause fire or explosion), strong acids, alkalis
Hazardous Polymerization: Does not occur
Decomposition Products: Toxic hydrogen bromide, hydrogen chloride, carbon monoxide, carbon dioxide, phosgene if burned
Reactivity: Minimal under standard conditions, increased by heat or incompatible chemicals

Toxicological Information

Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Acute Toxicity: LD50 (rat, oral): approximately 2000 mg/kg (estimated from similar halogenated aromatics)
Dermal Toxicity: No reliable data but may cause irritation on extended contact
Inhalation Toxicity: Exposure above 10 ppm causes nose and throat irritation, dizziness
Skin Corrosion/Irritation: Irritant effect
Eye Damage/Irritation: Strong irritant
Sensitization: Not documented for this compound
Chronic Effects: Prolonged or repeated contact may cause dermatitis
Carcinogenicity, Mutagenicity, Reproductive Toxicity: No information available, not listed by IARC, NTP, OSHA
Symptoms of Exposure: Burning, irritation, coughing, nausea, neurological effects (at high concentrations)

Ecological Information

Aquatic Toxicity: Toxic to aquatic organisms at moderate concentrations, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Slowly biodegradable; resists rapid breakdown in soil and water
Bioaccumulative Potential: May bioaccumulate in aquatic species due to high log Kow
Mobility in Soil: Limited, tends to bind to soil particles
Other Adverse Effects: Runoff may affect plant and microorganism health near disposal areas
Precautions: Avoid release to environment, follow applicable regulations for environmental protection

Disposal Considerations

Waste Treatment Methods: Burn in licensed chemical incinerator with afterburner and scrubber or deliver to licensed hazardous waste disposal firm
Container Handling: Rinse and destroy empty containers safely according to local/national authority standards
Disposal of Product: Collect and store waste liquid in properly labeled, closed containers for hazardous waste pickup
Contaminated Packaging: Dispose of as hazardous waste unless properly cleaned
Environmental Cautions: Do not dispose in household garbage, drains, or local landfill
Regulatory Requirements: Follow current local, national, and international regulations for disposal of hazardous organic chemicals

Transport Information

UN Number: UN 3082
UN Proper Shipping Name: Environmentally hazardous substance, liquid, n.o.s. (3-Bromochlorobenzene)
Transport Hazard Class: 9
Packing Group: III
Marine Pollutant: Yes
Transport Labels: Environmentally hazardous substance (fish and tree pictogram)
Special Transport Precautions: Prevent container damage and leaks, ensure upright secure position during transport
Transport Regulations: Refer to IMO/IMDG, IATA/ICAO, ADR/RID codes for specific rules

Regulatory Information

US TSCA Inventory: Listed
EU REACH Status: Registered or pre-registered for laboratory/research use
Labeling Requirements: GHS, local hazard communication standards apply (including pictograms and precautionary statements)
Federal and State Regulations: Subject to control as hazardous substance in many jurisdictions
Worker Safety: OSHA or similar national standards require provision of safety training, eye wash stations, and emergency showers
Environmental Regulations: Product may be regulated as hazardous waste or pollutant, check local guidelines
Restrictions: Only qualified personnel with appropriate PPE should handle product in non-consumer settings regulated by chemical safety codes